I'd say the 'wire' is one of these net-like things you put on your windows in hot areas to avoid flies and mosquitos coming in. In the same context I'd think the 'screen' is the window.
(like the first line indicated, he may be sitting on his desk just in front of the window, looking out - that would explain the whole setting.)
I'm no native speaker, but think 'plain' in this context means something like "you could hear the scream over the whole city."
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